Government Contract | Iowa
REAL TIME METABOLIC ANALYZERS

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Bid Information


Bid Alert No: 00000428007

Bid Title: REAL TIME METABOLIC ANALYZERS

Agency Bid No. Title: 63248

Received Date: 12/01/2015

Close Date: 12/09/2015

Purchase Type: Not Stated

Delivery Point: Ames, Iowa

Delivery Date: Not Stated

Special Notices: Bidder Preregistration

Specifications

Specifications include, but are not limited to:Lab 1: Researchers study metabolic function and mitochondrial ATP generation and their relationship to aging bymeasuring mitochondrial function and dynamics in cells from animals of continuously increasing age.Researchers require an assay platform that will allow the measurement of State 3 and State 4 mitochondrialrespiration (baseline and maximal during ATP production), as well as LD50 to Calcium loading. Researchers workwith mitochondrial samples that were isolated from live muscle cells. And the lab requests the analyzer withcapability of measuring mitochondrial function in a miniaturized and high-throughput manner with samples assmall as 10 micrograms of mitochondria, as well as the ability to program injections of substrates and inhibitorsin reproducible quantities. In addition, the lab also requires the capability of measuring glycolytic function in livecells, and the transition from glycolysis to mitochondrial respiration. We need an assay platform that measuresboth glycolysis and glycolytic reserve.Lab 2: Research primarily focuses on neurodegenerative disorders including Parkinson's disease. Researchersrequest an analyzer that allows simultaneous measurement of oxygen consumption rate (OCR) and extracellularacidification rate (ECAR) of living cells and tissues for measuring metabolic phenotype, mitochondrial respiration,glycolysis, and fatty acid oxidation. The lab is particularly interested in measuring key parameters of mitochondrialbioenergetics, a) basal instantaneous respiration rate, b) ATP-linked respiration and c) respiration capacity in cellculture and animal models of neurodegeneration.

Bid Related Documents

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Product Codes: 49520, 96246

Agency Information


Issuing Agency: Iowa State University

State: Iowa

Agency Type: State and Local

Contact: Yi Wu Purchasing Department, 3616 Administrative Services Building, Ames, Iowa, 50011

Phone: 515-294-1857

Email: yiwu@iastate.edu

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